TELEDYNE ISCO CombiFlash RF 200 System – Chromatography Unit

TELEDYNE ISCO CombiFlash RF 200 Automated Flash Chromatography System Model: RF 200 SN: 213A20220 Professionally deinstalled from working lab Powers On Includes: Comes with power cord and tubings Ships Fast and well packed! Teledyne ISCO CombiFlash® RF Automated Flash Chromatography System The Teledyne ISCO CombiFlash RF is a fully automated flash chromatography system designed for rapid, efficient purification of compounds from complex mixtures. Ideal for pharmaceutical, chemical, and research laboratories, the system simplifies the purification process through intelligent automation, user-friendly controls, and reliable performance. Key Features and Capabilities Fully Automated Chromatography Workflow Automates gradient formation, sample loading, column equilibration, elution, and fraction collectionâreducing manual intervention and improving reproducibility. Integrated Touchscreen Interface Features an intuitive, built-in touchscreen with graphical user interface (GUI) that allows users to program methods, monitor real-time progress, and easily adjust parameters. Variable Flow Rates and Pressure Control Offers variable flow rates (typically up to 200 mL/min) and supports pressures up to 200 psi, allowing compatibility with a broad range of columns and separation needs. UV and Optional ELSD Detection Standard system includes multi-wavelength UV detection (up to 4 channels); optional evaporative light scattering detector (ELSD) can be integrated for non-UV-active compounds. Wide Column Compatibility Supports a variety of Teledyne ISCO RediSep® columns, including normal-phase, reversed-phase, silica, C18, amino, and ion-exchange columns. Flexible Sample Injection Capable of loading samples via solid injection, liquid loop, or sample pump depending on the purification method and compound solubility. Automated Gradient Formation Built-in binary or quaternary solvent gradient mixing enables precise control over mobile phase composition during purification. Intelligent Peak Detection & Fraction Collection Software algorithms detect peaks and automatically trigger fraction collection based on UV absorbance thresholds, slope, or timeâensuring optimal recovery and purity. Solvent and Waste Monitoring Includes real-time solvent level monitoring and waste container management for safe and efficient operation. Applications Organic Synthesis â Purification of intermediates, final products, or crude reaction mixtures Natural Product Isolation â Separation of bioactive compounds from plant or microbial extracts Analytical Scale-Up â Bridging the gap between small-scale prep and production-scale purification Pharmaceutical R&D â Compound library generation, impurity isolation, and lead optimization Process Chemistry â Purifying multigram quantities of intermediates or products Technical Specifications (Typical) Flow Rate Range: Up to 200 mL/min (model dependent) Pressure Range: Up to 200 psi (13.8 bar) UV Detection: 200â400 nm standard (expandable); up to 4 wavelengths simultaneously Solvent Compatibility: Normal-phase and reversed-phase solvents Fraction Collection: Tube racks and bottles, configurable by volume or peak detection Display: Integrated touchscreen with user-friendly control interface Data Output: USB, Ethernet, or network storage compatible Dimensions & Weight: Varies by model and configuration (typically bench-top footprint) Advantages Reduces purification time compared to traditional column chromatography Minimizes solvent use through optimized gradients and automated controls Improves safety with closed solvent handling and real-time monitoring Increases reproducibility and purity with programmable methods and detection control Scalable platform with options for various throughput and complexity levels Summary The Teledyne ISCO CombiFlash RF is a robust and intelligent solution for laboratories seeking efficient, scalable, and user-friendly flash chromatography. Whether you're performing routine purifications or handling complex separation challenges, the CombiFlash RF system delivers consistent results with minimal effort.